
Alex Fabian
•Effectively managed a team of production engineers and development scientists tasked with starting up production in a brand... | Greater Tampa Bay Area, Greater Tampa Bay Area, United States
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Alex Fabian’s Emails al****@pf****.com
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Alex Fabian’s Location Greater Tampa Bay Area, Greater Tampa Bay Area, United States
Alex Fabian’s Expertise •Effectively managed a team of production engineers and development scientists tasked with starting up production in a brand new bio-processing facility. •Successfully directed the day to day operations of a production department employing a staff of over one hundred and manufacturing more than fifty active pharmaceutical ingredients (APIs). •Controlled the development, optimization and technology transfer of a new, environmentally friendly Dinoprostone process that resulted in a 5-fold yield increase while greatly simplifying the commercial route and significantly reducing waste. This process was awarded second place Pfizer Global Manufacturing (PGM) Green Chemistry Award. •Coordinated the development, optimization and implementation in the pilot plant of a fully continuous Celecoxib (Celebrex) process, and collaborated with the regulatory team tasked with the first continuous design-space filing with the Food and Drug Administration (FDA). The team was rewarded with the PGM Innovation Award. •Efficaciously headed a global team that developed a new second generation Sildenafil Citrate (Viagra) process that reduced the API’s cost by half while also substantially reducing processing time and waste. •Orchestrated an international team that re-engineered and implemented an optimized second generation hybrid (part continuous part batch) Pregabalin (Lyrica) process, resulting in savings of over 100 million per year and being able to meet increased customer demands. The team was awarded the PGM Innovation Award. •Developed, optimized and led the implementation in production of a second generation Methylprednisolone process which increased the yield by 35% while reducing processing times by 20%; a second generation Megestrol Acetate process that reduced processing times by 80% and solvent usage by 75%; a second generation 16α-Hydroxyprednisolone process that led to 35% cost savings and 50% processing time reduction.
Alex Fabian’s Current Industry Abbvie
Alex
Fabian’s Prior Industry
Sinteza
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Terapia
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Naeja Pharmaceutical
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Pharmacia
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Pfizer
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Valent Biosciences
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North America
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Alcami
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Abbvie
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Work Experience

Abbvie
Sr. Scientist Science & Technology API, Engineering Group -Retired
Sun Apr 01 2018 00:00:00 GMT+0000 (Coordinated Universal Time) — Sat Aug 01 2020 00:00:00 GMT+0000 (Coordinated Universal Time)
Alcami
Sr. Manager/Group Leader, Chemical Research and Development
Tue Nov 01 2016 00:00:00 GMT+0000 (Coordinated Universal Time) — Sun Oct 01 2017 00:00:00 GMT+0000 (Coordinated Universal Time)
North America
On vacation and traveling
Sun Nov 01 2015 00:00:00 GMT+0000 (Coordinated Universal Time) — Tue Nov 01 2016 00:00:00 GMT+0000 (Coordinated Universal Time)
Valent Biosciences
Technical Manager
Wed Oct 01 2014 00:00:00 GMT+0000 (Coordinated Universal Time) — Thu Oct 01 2015 00:00:00 GMT+0000 (Coordinated Universal Time)
Pfizer
Senior Principal Scientist
Fri Aug 01 2014 00:00:00 GMT+0000 (Coordinated Universal Time) — Wed Oct 01 2014 00:00:00 GMT+0000 (Coordinated Universal Time)
Pfizer
Principal Scientist
Wed Jan 01 2003 00:00:00 GMT+0000 (Coordinated Universal Time) — Fri Aug 01 2014 00:00:00 GMT+0000 (Coordinated Universal Time)
Pharmacia
Research Scientist
Tue Jan 01 2002 00:00:00 GMT+0000 (Coordinated Universal Time) — Wed Jan 01 2003 00:00:00 GMT+0000 (Coordinated Universal Time)
Naeja Pharmaceutical
Senior Research Scientist/Manager
Fri Jan 01 1999 00:00:00 GMT+0000 (Coordinated Universal Time) — Mon Jan 01 2001 00:00:00 GMT+0000 (Coordinated Universal Time)
Terapia
Sr. Director Production
Tue Jan 01 1991 00:00:00 GMT+0000 (Coordinated Universal Time) — Thu Jan 01 1998 00:00:00 GMT+0000 (Coordinated Universal Time)
Sinteza
Process Engineer
Fri Jan 01 1988 00:00:00 GMT+0000 (Coordinated Universal Time) — Tue Jan 01 1991 00:00:00 GMT+0000 (Coordinated Universal Time)