
David Grainger
I develop exciting new drugs, with novel mechanisms of action, challenging conventional wisdom on how drugs should be... | Cambridge, Cambridge, United Kingdom
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David Grainger’s Location Cambridge, Cambridge, United Kingdom
David Grainger’s Expertise I develop exciting new drugs, with novel mechanisms of action, challenging conventional wisdom on how drugs should be developed at every step. I am now Chief Innovation Officer at Centessa Pharmaceuticals (NASDAQ: CNTA), overseeing the research across our pipeline of 16 programs, which range from discovery to Ph3 clinical trials. I was Founding General Partner at Medicxi, one if Europe's largest and most successful Life Sciences Venture Capital groups, where I have acted as Chief Scientific Advisor since 2017 and am currently a Venture Advisor. I am currently a Director of more than a dozen biotech companies in the UK and US. Previously, I acted as CSO at XO1, developing an anticoagulant antibody. XO1 was sold to Janssen in March 2015, and also CSO at Funxional Therapeutics, a company developing novel small molecule anti-inflammatory agents sold to Boehringer Ingelheim in 2012, as well as CEO at Methuselah Health Inc, a company engaged in healthy ageing R&D. I also currently act as Executive Chairman at RxCelerate, a rapidly-growing out-sourced drug developer, with offices in the UK & US, which I founded in 2013 alongside Dr Jill Reckless.RxCelerate offers a turn-key drug discovery and development service, with expertise in both small-molecules and biologics through our proprietary Galaxy platform. Until 2011, I was an academic, based in Department of Medicine, Cambridge University, UK, where I led a group of about 10 scientists investigating the molecular mechanisms responsible for chronic inflammation in health and disease. I have published more than 70 primary publications, many in leading journals including Science, Nature and Nature Medicine. My career goal is to successfully integrate deep technical knowledge and a keen commercial perspective to ensure that the highest quality cutting edge research is effectively exploited to bring genuine healthcare benefits to the wider community. Specialties: In addition to technical expertise in drug discovery and early stage development (including US regulatory pathways to IND for therapeutics and 510(k) for diagnostics), I also have extensive experience in intellectual property management and strategy, as well drafting individual patent applications. I have been responsible for in- and out-licensing of healthcare technologies, for significant venture capital financing of several companies and for several mergers and acquisitions.
David Grainger’s Current Industry Centessa Pharmaceuticals
David
Grainger’s Prior Industry
Cambridge University
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Tcp Innovations
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Funxional Therapeutics
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Pronostics
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Index Ventures
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Total Scientific
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Xo1
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Rxcelerate
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Medicxi
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Centessa Pharmaceuticals
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Work Experience

Centessa Pharmaceuticals
Chief Innovation Officer
Fri Oct 01 2021 00:00:00 GMT+0000 (Coordinated Universal Time) — Mon Jan 01 2024 00:00:00 GMT+0000 (Coordinated Universal Time)
Medicxi
Partner
Mon Feb 01 2016 00:00:00 GMT+0000 (Coordinated Universal Time) — Present
Rxcelerate
Chairman
Tue Apr 01 2014 00:00:00 GMT+0000 (Coordinated Universal Time) — Present
Xo1
Chairman and CSO
Mon Apr 01 2013 00:00:00 GMT+0000 (Coordinated Universal Time) — Mon Jun 01 2015 00:00:00 GMT+0000 (Coordinated Universal Time)
Total Scientific
Executive Chairman
Fri Apr 01 2011 00:00:00 GMT+0000 (Coordinated Universal Time) — Sun Apr 01 2018 00:00:00 GMT+0000 (Coordinated Universal Time)
Index Ventures
Partner
Tue Jan 01 2008 00:00:00 GMT+0000 (Coordinated Universal Time) — Mon Feb 01 2016 00:00:00 GMT+0000 (Coordinated Universal Time)
Pronostics
Director and CSO
Sun Jan 01 2006 00:00:00 GMT+0000 (Coordinated Universal Time) — Tue Jan 01 2008 00:00:00 GMT+0000 (Coordinated Universal Time)
Funxional Therapeutics
Chief Scientific Officer
Sat Jan 01 2005 00:00:00 GMT+0000 (Coordinated Universal Time) — Fri Feb 01 2013 00:00:00 GMT+0000 (Coordinated Universal Time)
Tcp Innovations
CEO
Mon Jan 01 2001 00:00:00 GMT+0000 (Coordinated Universal Time) — Fri May 01 2015 00:00:00 GMT+0000 (Coordinated Universal Time)
Cambridge University
Principal Investigator
Sun Jan 01 1989 00:00:00 GMT+0000 (Coordinated Universal Time) — Thu Dec 01 2011 00:00:00 GMT+0000 (Coordinated Universal Time)