Jason Skudlarek
Highly motivated and team-oriented medicinal chemist with > 25 years of extensive experience and impact across a broad... | Norristown, Pennsylvania, United States
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Jason Skudlarek’s Emails ja****@me****.com
Jason Skudlarek’s Phone Numbers 1908423****
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Jason Skudlarek’s Location Norristown, Pennsylvania, United States
Jason Skudlarek’s Expertise Highly motivated and team-oriented medicinal chemist with > 25 years of extensive experience and impact across a broad range of medicinal chemistry programs and targets, including small molecule, prodrug, adjuvant lipid, and peptide design, synthesis, and SAR evaluation, complex multi-step synthesis, parallel library synthesis, scale-up, catalysis, and crystallization, all in close collaboration with other functional areas (e.g. PPDM, BPS, DPC, external CRO partners). Co-inventor on > 35 published patents. Strengths and skills include: lead identification and optimization, scaffold-hopping, pharmacophore model development through SAR analysis, and assessment/improvement of pharmacokinetic properties. Milligram to multi-kilogram synthesis; pharmacophore model development through SAR analysis; cGMP synthesis development; proficiency handling air sensitive organometallic compounds using an inert atmosphere/glove box and Schlenck techniques. Utilization of Biotage microwave systems and SymphonyX and CEM Liberty Blue peptide synthesizers; purification using flash chromatography, HPLC, Biotage, Gilson, and Isco purification systems (normal- and reversed-phase); analysis and characterization using NMR, FT-IR, Agilent/Waters/Shimadzu HPLC (including method development), UPLC, and GC; maintenance and repair of Agilent LC systems; highly experienced with LC/MS. Proficient with MS Word, Excel, PowerPoint, SciFinder, and Reaxys (CrossFire); experience with electronic laboratory notebooks and MOE. Patent literature searching, evaluation, and preparation.
Jason Skudlarek’s Current Industry Merck
Jason
Skudlarek’s Prior Industry
Hoechst Celanese
|
Magellan Labscardinal Health
|
Atherogenics
|
Metastatix
|
Emory Institute For Drug Development
|
Altiris Therapeutics
|
Merck
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Work Experience
Merck
Associate Principal Scientist
Tue Sep 01 2009 00:00:00 GMT+0000 (Coordinated Universal Time) — Present
Altiris Therapeutics
Scientist
Tue Jul 01 2008 00:00:00 GMT+0000 (Coordinated Universal Time) — Tue Sep 01 2009 00:00:00 GMT+0000 (Coordinated Universal Time)
Emory Institute For Drug Development
Senior Research Specialist
Tue Apr 01 2008 00:00:00 GMT+0000 (Coordinated Universal Time) — Tue Jul 01 2008 00:00:00 GMT+0000 (Coordinated Universal Time)
Metastatix
Scientist
Sun Jul 01 2007 00:00:00 GMT+0000 (Coordinated Universal Time) — Fri Feb 01 2008 00:00:00 GMT+0000 (Coordinated Universal Time)
Atherogenics
Scientist
Fri Feb 01 2002 00:00:00 GMT+0000 (Coordinated Universal Time) — Tue May 01 2007 00:00:00 GMT+0000 (Coordinated Universal Time)
Magellan Labscardinal Health
Chemist III
Fri Sep 01 2000 00:00:00 GMT+0000 (Coordinated Universal Time) — Fri Feb 01 2002 00:00:00 GMT+0000 (Coordinated Universal Time)
Hoechst Celanese
Co-op student
Fri Jan 01 1993 00:00:00 GMT+0000 (Coordinated Universal Time) — Mon Jan 01 1996 00:00:00 GMT+0000 (Coordinated Universal Time)Skills
Languages
Jason Skudlarek Email Addresses
Jason Skudlarek Phone Number
FAQ About Jason Skudlarek
-
Jason Skudlarek is located at
Norristown, Pennsylvania, United States -
Jason Skudlarek is a
Highly motivated and team-oriented medicinal chemist with > 25 years of extensive experience and impact across a broad range of medicinal chemistry programs and targets, including small molecule, prodrug, adjuvant lipid, and peptide design, synthesis, and SAR evaluation, complex multi-step synthesis, parallel library synthesis, scale-up, catalysis, and crystallization, all in close collaboration with other functional areas (e.g. PPDM, BPS, DPC, external CRO partners). Co-inventor on > 35 published patents. Strengths and skills include: lead identification and optimization, scaffold-hopping, pharmacophore model development through SAR analysis, and assessment/improvement of pharmacokinetic properties. Milligram to multi-kilogram synthesis; pharmacophore model development through SAR analysis; cGMP synthesis development; proficiency handling air sensitive organometallic compounds using an inert atmosphere/glove box and Schlenck techniques. Utilization of Biotage microwave systems and SymphonyX and CEM Liberty Blue peptide synthesizers; purification using flash chromatography, HPLC, Biotage, Gilson, and Isco purification systems (normal- and reversed-phase); analysis and characterization using NMR, FT-IR, Agilent/Waters/Shimadzu HPLC (including method development), UPLC, and GC; maintenance and repair of Agilent LC systems; highly experienced with LC/MS. Proficient with MS Word, Excel, PowerPoint, SciFinder, and Reaxys (CrossFire); experience with electronic laboratory notebooks and MOE. Patent literature searching, evaluation, and preparation. Merck -
Jason Skudlarek currently works in the
Merck -
Jason Skudlarek specializes in
Highly motivated and team-oriented medicinal chemist with > 25 years of extensive experience and impact across a broad range of medicinal chemistry programs and targets, including small molecule, prodrug, adjuvant lipid, and peptide design, synthesis, and SAR evaluation, complex multi-step synthesis, parallel library synthesis, scale-up, catalysis, and crystallization, all in close collaboration with other functional areas (e.g. PPDM, BPS, DPC, external CRO partners). Co-inventor on > 35 published patents. Strengths and skills include: lead identification and optimization, scaffold-hopping, pharmacophore model development through SAR analysis, and assessment/improvement of pharmacokinetic properties. Milligram to multi-kilogram synthesis; pharmacophore model development through SAR analysis; cGMP synthesis development; proficiency handling air sensitive organometallic compounds using an inert atmosphere/glove box and Schlenck techniques. Utilization of Biotage microwave systems and SymphonyX and CEM Liberty Blue peptide synthesizers; purification using flash chromatography, HPLC, Biotage, Gilson, and Isco purification systems (normal- and reversed-phase); analysis and characterization using NMR, FT-IR, Agilent/Waters/Shimadzu HPLC (including method development), UPLC, and GC; maintenance and repair of Agilent LC systems; highly experienced with LC/MS. Proficient with MS Word, Excel, PowerPoint, SciFinder, and Reaxys (CrossFire); experience with electronic laboratory notebooks and MOE. Patent literature searching, evaluation, and preparation. -
Jason Skudlarek speaks the following languages:
No languages available. -
Jason Skudlarek has prior experience in the following industries:
Altiris Therapeutics , Emory Institute For Drug Development , Metastatix , Atherogenics , Magellan Labscardinal Health , Hoechst Celanese -
Jason Skudlarek has the following professional experience:
Merck , Altiris Therapeutics , Emory Institute For Drug Development , Metastatix , Atherogenics , Magellan Labscardinal Health , Hoechst Celanese . -
You can view Jason Skudlarek’s
LinkedIn profile at LinkedIn URL. -
Jason Skudlarek’s work email addresses are
[email protected] . -
Jason Skudlarek works at
Merck
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