
Lars Weidolf
I started out as an industrial PhD student in 1980 and got my PhD on “Metabolites of Felodipine... | Greater Gothenburg Metropolitan Area, Greater Gothenburg Metropolitan Area, Sweden
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Lars Weidolf’s Emails la****@as****.com
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Lars Weidolf’s Location Greater Gothenburg Metropolitan Area, Greater Gothenburg Metropolitan Area, Sweden
Lars Weidolf’s Expertise I started out as an industrial PhD student in 1980 and got my PhD on “Metabolites of Felodipine – Analytical Methods for Quantitative and Qualitative studies” in 1985. This opened my eyes to the incredibly interesting field of drug metabolism, and set the scene for the next 34 years of my career. The name of our company has changed, as well as the organization on numerous occasions, but I have remained faithful to the science of drug metabolism all along. I have gained significant expertise in preclinical and clinical Phase I DMPK work. I’m an inventor of esomeprazole (Nexium) and have contributed to Regulatory submissions for other marketed products, e.g., omeprazole and felodipine. I am author and coauthor of about 50 peer reviewed papers, including three review articles and a book chapter. The main theme is biotransformation of drugs and drug candidates in late Drug Discovery and throughout Development. In 2003 I was appointed adjunct associate professor of biotransformation at Göteborg’s University. I am an expert on LC-MS(MS), use of H-3 and C-14 in metabolism studies, CoA mediated metabolism of carboxylic acid drugs, MIST, animal and human ADME studies, and in vitro methodology for biotransformation studies. I monitor in-house and out-sourced DMPK work, mentor and train colleagues etc. My experience, however, is so far limited to “small molecule” drugs. Our research is now focusing on various “new modality drugs”, e.g., oligonucleotide drugs, targeted conjugated oligonucleotides etc. Hence, the dominant focus of my work for the remainder of my career will be on the biotransformation of these drug types.
Lars Weidolf’s Current Industry Astrazeneca
Lars
Weidolf’s Prior Industry
Astrazeneca R And D Molndal
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Retired From Astrazeneca R And D Molndal
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Cornell University College Of Veterinary Medicine
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University Of Gothenburg
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Astrazeneca
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Work Experience

Astrazeneca
Retired
Wed Sep 01 2021 00:00:00 GMT+0000 (Coordinated Universal Time) — Present
University Of Gothenburg
Associate Professor
Sat Mar 01 2003 00:00:00 GMT+0000 (Coordinated Universal Time) — Present
Cornell University College Of Veterinary Medicine
Post doc
Sat Mar 01 1986 00:00:00 GMT+0000 (Coordinated Universal Time) — Sun Mar 01 1987 00:00:00 GMT+0000 (Coordinated Universal Time)
Retired From Astrazeneca R And D Molndal
Senior Principal Scientist Emeritus
Mon Oct 01 1979 00:00:00 GMT+0000 (Coordinated Universal Time) — Present
Astrazeneca R And D Molndal
Senior Principal Scientist
Sat Sep 01 1979 00:00:00 GMT+0000 (Coordinated Universal Time) — Present