
Naresh Kumar
Highly dynamic, accomplished scientist focusing on drug discovery in the area of immunology and immuno-oncology. • More than 20... | Greater Philadelphia, Greater Philadelphia, United States
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Naresh Kumar’s Location Greater Philadelphia, Greater Philadelphia, United States
Naresh Kumar’s Expertise Highly dynamic, accomplished scientist focusing on drug discovery in the area of immunology and immuno-oncology. • More than 20 years of post-doctoral drug discovery experience in both small and large molecule discovery spanning multiple therapeutic areas with 10 years in pharmaceutical drug development in immunology and immuno-oncology. • Led several programs as project leads with multiple candidate selection and two of them progressing to clinical PoC studies (CD226: NCT04099277 and TIGIT/PD1 bi-specific: NCT04911881). • Demonstrated history of novel drug discovery. Applied innovative approaches to identify two first-in-class molecules targeting key nodes in different therapeutic areas: auto-immunity (ROR-γ for Th17 biology) and immuno-oncology (CD226 agonist antibody for T cell activation). • Lead the team as a Next-gen Res Team Leader (NTL) of a “First-in-class” CD226 agonist antibody with Ph1 trials ongoing (NCT04099277), the NTL position in Lilly is modeled on the concept of CEO of small biotech companies. . • Translational drug discovery experience developing and utilizing immunoassays to identify clinical candidate immune-modulatory antibodies. • Areas of expertise include molecular, cellular and immuno-biology, interplay of immune co-stimulatory & co-inhibitory receptors, immuno-oncology, Th17 biology, drug discovery, assay development, signal transduction, metabolic disorders, diabetes, obesity, nuclear receptor biology, GPCR biology, in vivo studies, gene regulation. • Extensive experience in target discovery/validation, lead optimization and clinical candidate selection. • Exceptional team player with proven track record of interdisciplinary leading cross-functional teams and collaborations with academia and industry.
Naresh Kumar’s Current Industry Astrazeneca
Naresh
Kumar’s Prior Industry
Hp University
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National Institute Of Pharmaceutical Education And Research
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Duke University Medical Center And The Hamner Institute
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The Scripps Research Institute
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Eli Lilly
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The Janssen Pharmaceutical Companies Of Johnson And Johnson
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Astrazeneca
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Work Experience

Astrazeneca
Director Bioscience Immunology
Mon May 01 2023 00:00:00 GMT+0000 (Coordinated Universal Time) — Present
The Janssen Pharmaceutical Companies Of Johnson And Johnson
Associate Director
Thu Apr 01 2021 00:00:00 GMT+0000 (Coordinated Universal Time) — Sat Apr 01 2023 00:00:00 GMT+0000 (Coordinated Universal Time)
The Janssen Pharmaceutical Companies Of Johnson And Johnson
Principal Scientist
Thu Aug 01 2019 00:00:00 GMT+0000 (Coordinated Universal Time) — Thu Apr 01 2021 00:00:00 GMT+0000 (Coordinated Universal Time)
Eli Lilly
Senior Scientist/NTL, Cancer Immunobiology
Sun Feb 01 2015 00:00:00 GMT+0000 (Coordinated Universal Time) — Thu Aug 01 2019 00:00:00 GMT+0000 (Coordinated Universal Time)
Eli Lilly
Research Scientist
Wed Aug 01 2012 00:00:00 GMT+0000 (Coordinated Universal Time) — Thu Jan 01 2015 00:00:00 GMT+0000 (Coordinated Universal Time)
The Scripps Research Institute
Staff Scientist
Wed Oct 01 2008 00:00:00 GMT+0000 (Coordinated Universal Time) — Wed Aug 01 2012 00:00:00 GMT+0000 (Coordinated Universal Time)
Duke University Medical Center And The Hamner Institute
Post Doctoral Fellow
Sat Feb 01 2003 00:00:00 GMT+0000 (Coordinated Universal Time) — Mon Sep 01 2008 00:00:00 GMT+0000 (Coordinated Universal Time)
National Institute Of Pharmaceutical Education And Research
Research Fellow
Fri Jan 01 1999 00:00:00 GMT+0000 (Coordinated Universal Time) — Sun Dec 01 2002 00:00:00 GMT+0000 (Coordinated Universal Time)
Hp University
Master's student
Mon Jul 01 1996 00:00:00 GMT+0000 (Coordinated Universal Time) — Mon Jun 01 1998 00:00:00 GMT+0000 (Coordinated Universal Time)